O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes

Volume: 1863, Issue: 6, Pages: 1059 - 1069
Published: Jun 1, 2019
Abstract
O-GlcNAcylation is an important mechanism of diabetic complication. Retinoid homeostasis regulates cell-physiological functions through STRA6-retinol signaling. Therefore, we investigated whether O-GlcNAcylation disrupted STRA6-retinol signals in diabetes. Immunoprecipitation and proximity ligation assay were used to investigate O-GlcNAcylation of STRA6-retinol signals in kidneys of db/db and ob/ob mice. Western blot and immunohistochemistry...
Paper Details
Title
O-GlcNAcylation disrupts STRA6-retinol signals in kidneys of diabetes
Published Date
Jun 1, 2019
Volume
1863
Issue
6
Pages
1059 - 1069
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