Development of Zinc Chelating Resin Polymer Beads for the Removal of Cell-Free Hemoglobin
Abstract
Red blood cell (RBC) hemolysis is one of the most common storage lesions in packed RBCs (pRBC). Older units of pRBCs, especially those > 21 days old, have increasing levels of hemolysis leading to increased oxidative stress and premature platelet activation. This effect can mostly be attributed to the increase of cell-free hemoglobin (Hb). Therefore, removal of cell-free Hb from pRBCs prior to transfusion could mitigate these deleterious...
Paper Details
Title
Development of Zinc Chelating Resin Polymer Beads for the Removal of Cell-Free Hemoglobin
Published Date
Mar 27, 2019
Volume
47
Issue
6
Pages
1470 - 1478
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