CONVERGENT FUNCTIONAL GENOMICS APPROACH TO IDENTIFY GENES INVOLVED IN ATTENTION DEFICIT/HYPERACTIVITY DISORDER

The PGC + iPSYCH GWAS meta-analysis has led to the discovery of DNA variants associated with ADHD, but most of the heritability of this polygenic disorder is still missing. One of the main challenges is going from trait-associated variants to plausible causal genes and biological mechanisms. We propose an alternative approach to identify genes potentially involved in ADHD, focusing our attention on differentially expressed genes in Peripheral...