Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin
Abstract
The light-driven proton pump Coccomyxa subellipsoidea rhodopsin (CsR) provides-because of its high expression in heterologous host cells-an opportunity to study active proton transport under controlled electrochemical conditions. In this study, solving crystal structure of CsR at 2.0-Å resolution enabled us to identify distinct features of the membrane protein that determine ion transport directivity and voltage sensitivity. A specific hydrogen...
Paper Details
Title
Design of a light-gated proton channel based on the crystal structure of Coccomyxa rhodopsin
Published Date
Mar 19, 2019
Journal
Volume
12
Issue
573
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