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Correction to: Landscape of somatic mutations in 560 breast cancer whole-genome sequences (Nature, (2016), 534, 7605, (47-54), 10.1038/nature17676)

Published on Feb 7, 2019in Nature43.07
· DOI :10.1038/s41586-019-0883-2
Serena Nik-Zainal39
Estimated H-index: 39
(Cambridge University Hospitals NHS Foundation Trust),
Helen Davies46
Estimated H-index: 46
+ 85 AuthorsMichael R. Stratton139
Estimated H-index: 139
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Abstract
© 2019, Springer Nature Limited. In the Methods section of this Article, ‘greater than’ should have been ‘less than’ in the sentence ‘Putative regions of clustered rearrangements were identified as having an average inter-rearrangement distance that was at least 10 times greater than the whole-genome average for the individual sample. ’. The Article has not been corrected.
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Recent advances have revealed the vast molecular diversity of cancer. Detailed data has enabled powerful methods to sort tumors into groups with benefits for prognosis and treatment. We are still missing, however, a general theoretical framework to understand the diversity of tumor gene-expression and mutations. To address this, we present a framework based on multi-task evolution theory, using the fact that tumors evolve in the body, and that tumors are faced with multiple tasks that contribute...
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