Dissecting hiPSC-CM pacemaker function in a cardiac organoid model
Abstract
Biological pacemakers could be a promising alternative to electronic pacemakers and human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CM) may represent a suitable source for implantable cells. To further unravel this potential a thorough understanding of pacemaker function with regard to coupling processes both in the physiological and in the graft-host context is required. Here we developed a 2-component cardiac organoid model...
Paper Details
Title
Dissecting hiPSC-CM pacemaker function in a cardiac organoid model
Published Date
Jun 1, 2019
Journal
Volume
206
Pages
133 - 145
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Notes
History