Original paper
STAT 3 signalling pathway is implicated in keloid pathogenesis by preliminary transcriptome and open chromatin analyses
Abstract
Keloids are wounding‐induced fibroproliferative human tumor‐like skin scars of complex genetic makeup and poorly defined pathogenesis. To reveal dynamic epigenetic and transcriptome changes of keloid fibroblasts, we performed RNA ‐seq and ATAC ‐seq analysis on an early passage keloid fibroblast cell strain and its paired normal control fibroblasts. This keloid strain produced keloid‐like scars in a plasma clot‐based skin equivalent humanized...
Paper Details
Title
Published Date
Apr 1, 2019
Journal
Volume
28
Issue
4
Pages
480 - 484
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Notes
History