CT temporal subtraction improves early detection of bone metastases compared to SPECT.

Published on Oct 1, 2019in European Radiology3.962
· DOI :10.1007/s00330-019-06107-w
Koji Onoue1
Estimated H-index: 1
(Kyoto University),
Mizuho Nishio4
Estimated H-index: 4
(Kyoto University)
+ 10 AuthorsKaori Togashi62
Estimated H-index: 62
(Kyoto University)
Objectives To compare observer performance of detecting bone metastases between bone scintigraphy, including planar scan and single-photon emission computed tomography, and computed tomography (CT) temporal subtraction (TS).
  • References (26)
  • Citations (1)
📖 Papers frequently viewed together
92 Citations
14 Authors (Koji Onoue, ..., Kaori Togashi)
3 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
#1Ryo Sakamoto (Kyoto University)H-Index: 4
#2Masahiro Yakami (Kyoto University)H-Index: 6
Last. Kaori Togashi (Kyoto University)H-Index: 62
view all 12 authors...
Temporal subtraction images obtained with serial CT with nonrigid registration showed promise in the efficient detection of newly developed bone metastases.
8 CitationsSource
#1Ahmedin Jemal (ACS: American Cancer Society)H-Index: 106
#2Elizabeth Ward (ACS: American Cancer Society)H-Index: 72
Last. Hannah K. Weir (CDC: Centers for Disease Control and Prevention)H-Index: 24
view all 16 authors...
274 CitationsSource
#1Shingo Iwano (Nagoya University)H-Index: 19
#2Rintaro Ito (Nagoya University)H-Index: 5
Last. Shinji Naganawa (Nagoya University)H-Index: 42
view all 7 authors...
Purpose We developed an original, computer-aided diagnosis (CAD) software that subtracts the initial thoracic vertebral three-dimensional computed tomography (3D-CT) image from the follow-up 3D-CT image. The aim of this study was to investigate the efficacy of this CAD software during screening for vertebral metastases on follow-up CT images of primary lung cancer patients. Materials and Methods The interpretation experiment included 30 sets of follow-up CT scans in primary lung cancer patients ...
5 CitationsSource
Purpose This study was designed to assess the additional value of SPECT/CT of the trunk used in conjunction with conventional nuclear imaging and its effects on patient management in a large patient series.
72 CitationsSource
#1Nishikant Damle (AIIMS: All India Institute of Medical Sciences)H-Index: 7
#2Chandrasekhar Bal (AIIMS: All India Institute of Medical Sciences)H-Index: 25
Last. Sneh Lata (AIIMS: All India Institute of Medical Sciences)H-Index: 5
view all 7 authors...
Objectives We aimed to compare the role of 18F-fluoride PET/CT, FDG PET/CT and 99mTc-MDP bone scans in the detection of bone metastases in patients with lung, breast and prostate carcinoma.
78 CitationsSource
#1D. Andrew Loblaw (Sunnybrook Health Sciences Centre)H-Index: 9
#2Gunita Mitera (Sunnybrook Health Sciences Centre)H-Index: 11
Last. Normand Laperriere (UHN: University Health Network)H-Index: 17
view all 4 authors...
Purpose To update the 2005 Cancer Care Ontario practice guidelines for the diagnosis and treatment of adult patients with a suspected or confirmed diagnosis of extradural malignant spinal cord compression (MESCC). Methods A review and analysis of data published from January 2004 to May 2011. The systematic literature review included published randomized control trials (RCTs), systematic reviews, meta-analyses, and prospective/retrospective studies. Results An RCT of radiation therapy (RT) with o...
72 CitationsSource
#2Ya-Yu TsaiH-Index: 1
Last. S.E. HoofeH-Index: 27
view all 3 authors...
Background: Bone metastases occur frequently in patients with advanced cancer and are a serious complication of cancer. The decision to treat is often individualized, based on each patient’s clinical presentation, life expectancy, and quality of life. Methods: We reviewed the current literature pertaining to management of metastatic disease to bone, and the medical, radiotherapeutic, and surgical treatment options for management of bone metastasis are discussed. Results: Current management of sk...
40 CitationsSource
Nuclear medicine in the United States has grown because of advances in technology, including hybrid imaging, the introduction of new radiopharmaceuticals for diagnosis and therapy, and the development of molecular imaging based on the tracer principle, which is not based on radioisotopes. Continued growth of the field will require cost-effectiveness data and evidence that nuclear medicine procedures affect patients’ outcomes. Nuclear medicine physicians and radiologists will need more training i...
23 CitationsSource
#1Ukihide Tateishi (YCU: Yokohama City University)H-Index: 35
#2SatoshiMorita (YCU: Yokohama City University)H-Index: 46
Last. E. Edmund Kim (University of Texas MD Anderson Cancer Center)H-Index: 37
view all 10 authors...
Purpose The aim of this study was to assess the diagnostic performance of 18F-Fluoride positron emission tomography (PET) or positron emission tomography/computed tomography (PET/CT) compared with bone scintigraphy (BS) planar or BS planar and single photon emission computed tomography (SPECT) in evaluating patients with metastatic bone tumor.
56 CitationsSource
#1Ruoh-Fang YenH-Index: 29
#2Chih Yu ChenH-Index: 7
Last. Rong-SenYangH-Index: 45
view all 10 authors...
Abstract The aim of this prospective study is to evaluate the diagnostic and prognostic usefulness of F-18 sodium fluoride (NaF) positron emission tomography-computed tomography (PET-CT) relative to Tc-99m methylene diphosphonate (MDP) planar bone scintigraphy with no CT (BS) for hepatocellular carcinoma (HCC) patients with suspicious bone metastasis. Both Tc-99m MDP BS and F-18 NaF PET-CT were performed for 34 consecutive Taiwanese HCC patients (five female and 29 male; mean age, 61.0+/-12.0 ye...
40 CitationsSource
Cited By1
#1M SierenH-Index: 1
view all 12 authors...
The diagnostic reading of follow-up low-dose whole-body computed tomography (WBCT) examinations in patients with multiple myeloma (MM) is a demanding process. This study aimed to evaluate the diagnostic accuracy and benefit of a novel software program providing rapid-subtraction maps for bone lesion change detection. Sixty patients (66 years ± 10 years) receiving 120 WBCT examinations for follow-up evaluation of MM bone disease were identified from our imaging archive. The median follow-up time ...
#1Koji Onoue (Kyoto University)H-Index: 1
#2Mizuho Nishio (Kyoto University)H-Index: 4
Last. Kaori Togashi (Kyoto University)H-Index: 62
view all 14 authors...