Angiotensin-converting-enzyme inhibitors in hemodynamic congestion: a meta-analysis of early studies

Major clinical trials have shown that angiotensin-converting enzyme (ACE) inhibitors reduce mortality and morbidity in congestive heart failure (HF). Prior to these seminal findings hemodynamic effects of ACE inhibitors were examined in small studies. We aimed to review these studies systematically and meta-analyze the effects of ACE inhibitors on hemodynamics in HF. We identified studies investigating the acute hemodynamic effect of ACE...