Glucocorticoids pharmacology and their application in the treatment of childhood-onset systemic lupus erythematosus
Volume: 49, Issue: 2, Pages: 251 - 259
Published: Oct 1, 2019
Abstract
Glucocorticoids are potent anti-inflammatory and immunosuppressant medications and remain the mainstay of systemic lupus erythematosus (SLE) therapy. The potency of a specific glucocorticoid, i.e., the dose of glucocorticoid that is required to produce a specific effect, is dependent on its pharmacokinetic (PK) and pharmacodynamic (PD) properties. In this review, we summarize the PK/PD properties of commonly used glucocorticoids in an attempt to...
Paper Details
Title
Glucocorticoids pharmacology and their application in the treatment of childhood-onset systemic lupus erythematosus
Published Date
Oct 1, 2019
Volume
49
Issue
2
Pages
251 - 259
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