Review paper
Mitochondria in early development: linking the microenvironment, metabolism and the epigenome
Abstract
Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage-specific restructuring and redistribution during oocyte maturation and preimplantation embryo development, necessary to support key developmental events. Mitochondria also fulfil a wide range of functions beyond ATP synthesis, including the production of intracellular...
Paper Details
Title
Mitochondria in early development: linking the microenvironment, metabolism and the epigenome
Published Date
May 1, 2019
Journal
Volume
157
Issue
5
Pages
R159 - R179
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