Collateral damage and CRISPR genome editing
Abstract
The simplicity and the versatility of clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR-Cas) systems have enabled the genetic modification of virtually every organism and offer immense therapeutic potential for the treatment of human disease. Although these systems may function efficiently within eukaryotic cells, there remain concerns about the accuracy of Cas endonuclease effectors and their use for...
Paper Details
Title
Collateral damage and CRISPR genome editing
Published Date
Mar 14, 2019
Journal
Volume
15
Issue
3
Pages
e1007994 - e1007994
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Notes
History