Network-based prediction of drug combinations
Abstract
Drug combinations, offering increased therapeutic efficacy and reduced toxicity, play an important role in treating multiple complex diseases. Yet, our ability to identify and validate effective combinations is limited by a combinatorial explosion, driven by both the large number of drug pairs as well as dosage combinations. Here we propose a network-based methodology to identify clinically efficacious drug combinations for specific diseases. By...
Paper Details
Title
Network-based prediction of drug combinations
Published Date
Mar 13, 2019
Journal
Volume
10
Issue
1
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