Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors
Abstract
Recent studies have demonstrated that human neutrophil elastase (HNE) can be used as marker for inflammation/infection of chronic wounds since it was found to be present in high concentration in exudate collected from chronic wounds. Biosensors used in wound care benefit from a chromogenic signalling due to the readiness of signal interpretation, but the most common use faint yellow chromogenic molecules such as p-nitroaniline (pNa). In...
Paper Details
Title
Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors
Published Date
Jun 1, 2019
Journal
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History