Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors

Published: Jun 1, 2019
Abstract
Recent studies have demonstrated that human neutrophil elastase (HNE) can be used as marker for inflammation/infection of chronic wounds since it was found to be present in high concentration in exudate collected from chronic wounds. Biosensors used in wound care benefit from a chromogenic signalling due to the readiness of signal interpretation, but the most common use faint yellow chromogenic molecules such as p-nitroaniline (pNa). In...
Paper Details
Title
Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors
Published Date
Jun 1, 2019
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