Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients
Abstract
Background
Resistance to immune checkpoint inhibitors (ICIs) has been linked to local immunosuppression independent of major ICI targets (e.g., PD-1). Clinical experience with response prediction based on PD-L1 expression suggests that other factors influence sensitivity to ICIs in non-small cell lung cancer (NSCLC) patients.Methods
Tumor specimens from 120 NSCLC patients from 10 institutions were evaluated for PD-L1...Paper Details
Title
Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients
Published Date
Feb 1, 2019
Volume
7
Issue
1
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Notes
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