Effects of chronic REM sleep deprivation on lipocalin-2, nitric oxide synthase-3, interleukin-6 and cardiotrophin-1 levels: an experimental rat model

The purpose of this study was to investigate the effects of chronic rapid eye movement sleep deprivation on cardiovascular system using blood levels of lipocalin-2, nitric oxide synthase-3, interleukin-6, and cardiotrophin-1. We included sixteen Wistar Albino rats of 300–350 g weight in the study. To create a chronic rapid eye movement sleep deprivation, we used water tanks with platform including modified multiple sleep deprivation platforms,...