Targeting growth hormone function: strategies and therapeutic applications.
Abstract
Human growth hormone (GH) is a classical pituitary endocrine hormone that is essential for normal postnatal growth and has pleiotropic effects across multiple physiological systems. GH is also expressed in extrapituitary tissues and has localized autocrine/paracrine effects at these sites. In adults, hypersecretion of GH causes acromegaly, and strategies that block the release of GH or that inhibit GH receptor (GHR) activation are the primary...
Paper Details
Title
Targeting growth hormone function: strategies and therapeutic applications.
Published Date
Feb 8, 2019
Volume
4
Issue
1
Pages
3
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