Radiomic analysis of contrast-enhanced CT predicts microvascular invasion and outcome in hepatocellular carcinoma

•We identified 8 MVI preoperative risk factors in HCC, including radiomic features. •Radiomic features do not provide significant added value to radiologist scores. •A model integrating clinic-radiologic and radiomic features demonstrates good performance for predicting MVI. Background & Aims Microvascular invasion (MVI) impairs surgical outcomes in patients with hepatocellular carcinoma (HCC). As there is no single highly reliable factor to...