Construction of porous sponge-like PVA-CMC-PEG hydrogels with pH-sensitivity via phase separation for wound dressing

AbstarctTo improve mechanical strength, polyvinyl alcohol hydrogels were often prepared through freeze-thaw method. However, they usually exhibited micropores limiting their applications. Hence, macroporous polyvinyl alcohol-carboxymethyl cellulose-polyethylene glycol (PVA-CMC-PEG) hydrogels were prepared through phase separation. Physical properties and biocompatibility experiments were carried. Results indicated that PVA-CMC-PEG hydrogel had...