Abstract P106: Genetically Determined Fibrinogen, Gamma Prime Fibrinogen and Risk of Venous Thromboembolism and Ischemic Stroke: Evidence From Mendelian Randomization
Abstract
Introduction: Fibrinogen is a key component of the coagulation cascade, and variation in its circulating levels may contribute to thrombotic diseases, such as venous thromboembolism (VTE) and ischemic stroke. Methods: Two-sample Mendelian randomization (MR) was applied to estimate the causal effect of circulating fibrinogen and its isoform, gamma prime fibrinogen, on risk of VTE and ischemic stroke subtypes using summary statistics from...
Paper Details
Title
Abstract P106: Genetically Determined Fibrinogen, Gamma Prime Fibrinogen and Risk of Venous Thromboembolism and Ischemic Stroke: Evidence From Mendelian Randomization
Published Date
Mar 5, 2019
Journal
Volume
139
Issue
Suppl_1
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