DEFOR: depth- and frequency-based somatic copy number alteration detector
Abstract
Motivation Detection of somatic copy number alterations (SCNAs) using high-throughput sequencing has become popular because of rapid developments in sequencing technology. Existing methods do not perform well in calling SCNAs for the unstable tumor genomes. Results We developed a new method, DEFOR, to detect SCNAs in tumor samples from exome-sequencing data. The evaluation showed that DEFOR has a higher accuracy for SCNA detection from exome...
Paper Details
Title
DEFOR: depth- and frequency-based somatic copy number alteration detector
Published Date
Mar 12, 2019
Journal
Volume
35
Issue
19
Pages
3824 - 3825
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Notes
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