Contractile Forces in Platelet Aggregates Under Microfluidic Shear Gradients Reflect Platelet Inhibition and Bleeding Risk

Volume: 10, Issue: 1, Pages: 1204 - 1204
Published: Mar 13, 2019
Abstract
Platelets contract forcefully after their activation, contributing to the strength and stability of platelet aggregates and fibrin clots during blood coagulation. Viscoelastic approaches can be used to assess platelet-induced clot strengthening, but they require thrombin and fibrin generation and are unable to measure platelet forces directly. Here, we report a rapid, microfluidic approach for measuring the contractile force of platelet...
Paper Details
Title
Contractile Forces in Platelet Aggregates Under Microfluidic Shear Gradients Reflect Platelet Inhibition and Bleeding Risk
Published Date
Mar 13, 2019
Volume
10
Issue
1
Pages
1204 - 1204
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