Modelling Protein Synthesis as A Biomarker in Fragile X Syndrome Patient-Derived Cells
Abstract
The most conserved molecular phenotype of Fragile X Syndrome (FXS) is aberrant protein synthesis. This has been validated in a variety of experimental model systems from zebrafish to rats, patient-derived lymphoblasts and fibroblasts. With the advent of personalized medicine paradigms, patient-derived cells and their derivatives are gaining more translational importance, not only to model disease in a dish, but also for biomarker discovery. Here...
Paper Details
Title
Modelling Protein Synthesis as A Biomarker in Fragile X Syndrome Patient-Derived Cells
Published Date
Mar 11, 2019
Journal
Volume
9
Issue
3
Pages
59 - 59
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