A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring
Abstract
Immune responses generally decline with age. However, the dynamics of this process at the individual level have not been characterized, hindering quantification of an individual's immune age. Here, we use multiple 'omics' technologies to capture population- and individual-level changes in the human immune system of 135 healthy adult individuals of different ages sampled longitudinally over a nine-year period. We observed high inter-individual...
Paper Details
Title
A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring
Published Date
Mar 1, 2019
Journal
Volume
25
Issue
3
Pages
487 - 495
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