Abstract 217: TBX5 ^Clover2 /NKX2-5 ^TagRFP hiPSCs for Simultaneously Isolating Lineage-Specific Cardiovascular Cells

In vertebrate, the heart is the first organ to develop, comprises multiple highly specialized cell types arising from different lineages. Early animal studies have identified two cardiac lineages: the first and second heart fields which contribute to the four-chamber heart formation. These cardiac progenitor cells develop into different parts of the heart and any perturbation of them frequently leads to congenital heart disease. However, given...