RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives
Volume: 38, Issue: 1
Published: Jan 8, 2019
Abstract
RANKL/RANK/OPG system consists of three essential signaling molecules: i) the receptor activator of nuclear factor (NF)-kB-ligand (RANKL), ii) the receptor activator of NF-kB (RANK), and iii) the soluble decoy receptor osteoprotegerin (OPG). Although this system is critical for the regulation of osteoclast differentiation/activation and calcium release from the skeleton, different studies have elucidated its specific role in mammary gland...
Paper Details
Title
RANKL/RANK/OPG system beyond bone remodeling: involvement in breast cancer and clinical perspectives
Published Date
Jan 8, 2019
Volume
38
Issue
1
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