Abstract 549: Interleukin-6 Trans-Signaling in Acute Myocardial Infarction in Male BALB/c Mice
Abstract
Interleukin-6 (IL-6) is a pleiotropic cytokine historically associated with development and/or maintenance of cardiovascular disease (CVD). Despite this long-standing association, the discrete roles of IL-6 on the pathogenesis or severity of CVD and notably acute myocardial infarction (AMI) remain unclear. Dogma contends that IL-6 mediates effects largely through direct interaction with a membrane-bound IL-6 receptor (IL-6R) on leukocytes and...
Paper Details
Title
Abstract 549: Interleukin-6 Trans-Signaling in Acute Myocardial Infarction in Male BALB/c Mice
Published Date
Aug 3, 2018
Journal
Volume
123
Issue
Suppl_1
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