Validating psychosocial pathways of risk between neuroticism and late life depression using a polygenic score approach.
Abstract
Neuroticism is a stable and heritable personality trait that is strongly linked to depression. Yet, little is known about its association with late life depression, as well as how neuroticism eventuates into depression. This study used data from the Wisconsin Longitudinal Study (WLS; N = 4,877) to examine the direct and indirect effects of neuroticism on late life depression at 3 points in the life course-ages 53, 64, and 71-via stressful life...
Paper Details
Title
Validating psychosocial pathways of risk between neuroticism and late life depression using a polygenic score approach.
Published Date
Apr 1, 2019
Volume
128
Issue
3
Pages
200 - 211
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