Small-Animal PET/CT Imaging of Local and Systemic Immune Response Using 64Cu-αCD11b
Abstract
Current noninvasive imaging methods for monitoring immune response were largely developed for interrogation of the local reaction. This study developed the radiotracer 64Cu-labeled anti-CD11b (64Cu-αCD11b) for longitudinal assessment of local and systemic immune response involving mobilization of CD11b+ myeloid cells by small-animal PET/CT. Methods: Acute or chronic inflammation in the ears of BALB/c mice was induced by...
Paper Details
Title
Small-Animal PET/CT Imaging of Local and Systemic Immune Response Using 64Cu-αCD11b
Published Date
Feb 22, 2019
Volume
60
Issue
9
Pages
1317 - 1324
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