A case‐comparison study of pregnant women with mitochondrial disease – what to expect?

Mitochondrial disease is a disorder of energy metabolism that affects 1 in 4300 adults in the UK. Pregnancy is associated with physiological demands that have implications for energy metabolism. We were interested to know how pregnancy was affected in women with mitochondrial disease, particularly those with the most common pathogenic mutation m.3243A>G.Retrospective case-comparison study.Sixty-seven women with genetically confirmed...