Strategies for Managing Intraoperative Discovery of Limited Colorectal Peritoneal Metastases.

Published on May 1, 2019in Annals of Surgical Oncology3.681
· DOI :10.1245/s10434-019-07225-x
A. Mariani2
Estimated H-index: 2
Maximiliano Gelli4
Estimated H-index: 4
+ 5 AuthorsDiane Goéré34
Estimated H-index: 34
Background Management of limited synchronous colorectal peritoneal metastases (CRPM) is critical to outcome. Resection of the primary tumor and CRPM can be performed concurrently, followed by hyperthermic intraperitoneal chemotherapy (HIPEC) either immediately, during the same procedure (one-stage), or during a systematic second-stage procedure (two-stage).
  • References (21)
  • Citations (1)
#1François QuenetH-Index: 25
#2Dominique EliasH-Index: 82
Last. Olivier GlehenH-Index: 46
view all 17 authors...
LBA3503Background: Promising results have been obtained during the last decade using cytoreductive surgery (CRS) plus HIPEC for selected patients with colorectal PC who are amenable to complete macroscopic resection. This is the first trial to evaluate the specific role of HIPEC, after CRS, for the treatment of PC of colorectal origin. Methods: Prodige 7 is a randomized phase III, multicenter trial. Patients with histologically proven and isolated PC, peritoneal cancer index (PCI) ≤25 were eligi...
66 CitationsSource
#1Diane Goéré (Institut Gustave Roussy)H-Index: 34
#2Olivier GlehenH-Index: 46
Last. ProdigeH-Index: 1
view all 10 authors...
3531Background: Complete cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) allow to prolong survival in patients with colorectal peritoneal metastases (CRPM)...
9 CitationsSource
#1Nikolaos Machairas (UoA: National and Kapodistrian University of Athens)H-Index: 7
#2Petros Charalampoudis (UoA: National and Kapodistrian University of Athens)H-Index: 5
Last. Georgios C. Sotiropoulos (UoA: National and Kapodistrian University of Athens)H-Index: 9
view all 7 authors...
Treatment options for patients with gastric cancer (GC) are based on tumor staging and resectability. Although only surgery provides improved survival, resection is contraindicated and should be avoided in the presence of intra-abdominal disease stage M1 (liver, peritoneal, or nonlocal lymph node metastases). Thus, a detailed and precise evaluation is imperative for optimal treatment. Staging laparoscopy (SL) constitutes a major tool in the accurate diagnosis of several types of cancers, includi...
7 CitationsSource
#1Charlotte E. L. Klaver (UvA: University of Amsterdam)H-Index: 5
#2H. Groenen (UvA: University of Amsterdam)H-Index: 1
Last. Pieter J. Tanis (UvA: University of Amsterdam)H-Index: 22
view all 6 authors...
AIM: This systematic review aimed to provide an overview of (inter)national guidelines on the treatment of peritoneal metastases of colorectal cancer origin (PMCRC) and to determine the degree of consensus and available evidence with identification of topics for future research. METHOD: A systematic search of MEDLINE, Embase, PubMed as well as Tripdatabase, National Guideline Clearinghouse, BMJ Best Practice and Guidelines International Network was performed to identify (inter)national guideline...
19 CitationsSource
#1Jan Franko (Mercy Medical Center (Baltimore, Maryland))H-Index: 6
#2Qian D Shi (Mayo Clinic)H-Index: 24
Last. Axel F Grothey (Mayo Clinic)H-Index: 61
view all 20 authors...
Summary Background Patients with peritoneal metastatic colorectal cancer have reduced overall survival compared with patients with metastatic colorectal cancer without peritoneal involvement. Here we further investigated the effect of the number and location of metastases in patients receiving first-line systemic chemotherapy. Methods We analysed individual patient data for previously untreated patients enrolled in 14 phase 3 randomised trials done between 1997 and 2008. Trials were included if ...
88 CitationsSource
#1Julie Navez (Cliniques Universitaires Saint-Luc)H-Index: 6
#2Christophe Remue (Cliniques Universitaires Saint-Luc)H-Index: 9
Last. Nicolas Jabbour (Cliniques Universitaires Saint-Luc)H-Index: 28
view all 11 authors...
Background Chemotherapeutic advances have enabled successful cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) expansion in treating metastatic colorectal cancer.
9 CitationsSource
#1Haythem Najah (Paris Diderot University)H-Index: 3
#2Réa Lo Dico (Paris Diderot University)H-Index: 3
Last. Marc Pocard (Paris Diderot University)H-Index: 10
view all 6 authors...
Objective To show the feasibility and the safety of peritoneal carcinomatosis (PC) evaluation by single-incision flexible endoscopy (SIFE) and to compare it to single-incision rigid endoscopy (SIRE).
15 CitationsSource
#1V. Leung (UNSW: University of New South Wales)H-Index: 2
#2N. Huang (UNSW: University of New South Wales)H-Index: 1
Last. David L. Morris (UNSW: University of New South Wales)H-Index: 65
view all 4 authors...
Abstract Objective Determine what portion of colorectal cancer (CRC) patients with peritoneal metastases (PM) undergoing peritonectomy would have been identified/treated if second-look surgery protocol existed for high-risk primary tumours. Background The prognosis of CRC PM greatly improves following peritonectomy/HIPEC. Survival remains dependent upon stage of PM and there is some knowledge of high-risk factors for its development. Subsequently, there is interest in routine second-look laparot...
3 CitationsSource
#1Dominique EliasH-Index: 82
#2Matthieu FaronH-Index: 9
Last. Diane GoéréH-Index: 34
view all 9 authors...
PURPOSE: To analyze and compare survival in patients operated for colorectal liver metastases (LM) with that in patients optimally resected for peritoneal metastases (PM). PATIENTS AND METHODS: This study concerns 287 patients with LM and 119 patients with PM treated with surgery plus chemotherapy between 1993 and 2009, excluding patients presenting both LM and PM. RESULTS: Mortality (respectively, 2.7% and 4.2%), morbidity (respectively, 11% and 17%), and 5-year overall survival (OS) rates (res...
43 CitationsSource
#1H.J. BraamH-Index: 10
#2Djamila BoermaH-Index: 26
Last. Bert van RamshorstH-Index: 38
view all 4 authors...
Abstract Aim To compare the clinical outcome of a one-stage, primary tumour resection and hyperthermic intraperitoneal chemotherapy (HIPEC) procedure, versus a two-stage procedure of tumour resection and secondary HIPEC in colorectal cancer (CRC) patients with synchronous peritoneal carcinomatosis. Methods A prospective database of all patients treated with HIPEC in the St. Antonius Hospital in the Netherlands between 2005 and 2012 was analysed. Results A total of 72 patients with synchronous pe...
16 CitationsSource
Cited By1
#1Olivier Glehen (University of Lyon)H-Index: 46
#2Vahan Kepenekian (University of Lyon)H-Index: 7
Last. François-Noël Gilly (University of Lyon)H-Index: 16
view all 10 authors...
Resume Les tumeurs primitives malignes du peritoine et les metastases ou carcinoses peritoneales ont ete longtemps considerees comme un stade metastatique terminal. Le developpement de nouvelles techniques de chirurgie de cytoreduction et peritonectomies, de chimiotherapie intraperitoneale associee ou non a l’hyperthermie, la mise en place de centres specialises dans la prise en charge de ces pathologies a considerablement modifie le pronostic de ces pathologies. Autrefois condamnes a court term...