Bence-Jones Proteins and Light Chains of Immunoglobulins

Considerable progress in our understanding of the functional implications of the immunochemical, biochemical, physicochemical, metabolic, and genetic properties of normal immunoglobulins has been achieved through the study of Bence-Jones proteins, myeloma proteins, Waldenström macroglobulins, and their subunits. These homogeneous proteins are produced by neoplastic immunoglobulin-synthesizing cells characteristically present in the bone marrow...