Synthesis, characterization and cytotoxic activity of diorganotin complexes with Schiff base derived from salicylaldehyde and l-tyrosine

Seven diorganotin complexes with the Schiff bases derived from salicylaldehyde and l-tyrosine, R2Sn[2-O-5-XC6H3CH = NCH(CH2C6 H4OH-4)COO] (X = H (1), Br (2); R = Me (a), Et (b), Bu (c), Cy (cyclohexyl) (d)), were synthesized and characterized by elemental analysis, IR, 1H and 13C NMR spectra, and the single-crystal X-ray diffraction. In methanol, the racemization of chiral center of l-tyrosinate fragment occurred and the racemic products were...