Circadian clock genes and circadian phenotypes in patients with myocardial infarction

Human physiological activities and diseases are under the control of the circadian rhythm. There are strong epidemiological associations between disrupted circadian rhythms, sleep duration and diseases. Sleep disorders are associated with vascular outcomes, such as myocardial infarction (MI). We conducted an association study of genotype-phenotype interaction, to determine which circadian clock gene variants might be associated with the...