Treatment-induced changes of lymphocyte subsets in patients with adenoid cystic carcinoma of the head and neck

Adenoid cystic carcinoma (ACC) of the head and neck is a rare and highly malignant tumor, characterized by perineural growth and early distant metastases. The composition of immune cells in the peripheral blood and the tumor microenvironment is critical to tumor growth and control. However, little is known about the frequency and function of the relevant immune cell subsets in this entity. In ACC patients (n = 11) and matched healthy donors (n =...