Identification of atheroprone shear stress responsive regulatory elements in endothelial cells
Abstract
Oscillatory shear stress (OSS) is an atheroprone haemodynamic force that occurs in areas of vessel irregularities and is implicated in the pathogenesis of atherosclerosis. Changes in signalling and transcriptional programme in response to OSS have been vigorously studied; however, the underlying changes in the chromatin landscape controlling transcription remain to be elucidated. Here, we investigated the changes in the regulatory element (RE)...
Paper Details
Title
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells
Published Date
Feb 20, 2019
Journal
Volume
115
Issue
10
Pages
1487 - 1499
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