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doi.org/10.1016/j.tiv.2019.02.022

Effect of the kaurenoic acid on genotoxicity and cell cycle progression in cervical cancer cells lines

..., Carlos Alberto Machado da Rocha
5
Toxicology in Vitro3.20
Volume: 57, Pages: 126 - 131
Published: Jun 1, 2019
Abstract
• Toxicity of kaurenoic acid (KA) was evaluated in three cervical cancer cell lines: HeLa, CaSki and C33A. • KA showed a strong positive correlation with DNA damage and micronuclei frequency. • At high concentrations, the KA inhibited the expression of E6 and E7 HPV genes. • The assays pointed to the possibility of using KA as feedstock for therapeutic agents against cervical cancer with...
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Paper Details
Title
Effect of the kaurenoic acid on genotoxicity and cell cycle progression in cervical cancer cells lines
DOI
doi.org/10.1016/j.tiv.2019.02.022
Published Date
Jun 1, 2019
Journal
Toxicology in Vitro
Volume
57
Pages
126 - 131
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