The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Abstract
Ageing constitutes the most important risk factor for all major chronic ailments, including malignant, cardiovascular and neurodegenerative diseases. However, behavioural and pharmacological interventions with feasible potential to promote health upon ageing remain rare. Here we report the identification of the flavonoid 4,4'-dimethoxychalcone (DMC) as a natural compound with anti-ageing properties. External DMC administration extends the...
Paper Details
Title
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Published Date
Feb 19, 2019
Journal
Volume
10
Issue
1
Pages
651 - 651
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