Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

Jenny van Dongen; Nuno R. Zilhão; Karen Sugden; Eilis Hannon; Jonathan Mill; Avshalom Caspi; Jessica Agnew-Blais; Louise Arseneault; David L. Corcoran; Terrie E. Moffitt; Barbara Franke; Dorret I. Boomsma

doi:https://doi.org/10.1016/j.biopsych.2019.02.016

doi.org/10.1016/j.biopsych.2019.02.016

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

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..., Dorret I. Boomsma

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Biological Psychiatry10.60

Volume: 86, Issue: 8, Pages: 599 - 607

Published: Oct 1, 2019

Abstract

BackgroundPrevious studies have reported associations between attention-deficit/hyperactivity disorder symptoms and DNA methylation in children. We report the first epigenome-wide association study meta-analysis of adult attention-deficit/hyperactivity disorder symptoms, based on peripheral blood DNA methylation (Infinium HumanMethylation450K array) in three population-based adult cohorts.MethodsAn epigenome-wide association study was performed...

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Paper Details

Title

Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults

DOI

doi.org/10.1016/j.biopsych.2019.02.016

Published Date

Oct 1, 2019

Journal

Biological Psychiatry

Volume

86

Issue

8

Pages

599 - 607

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