Rhinacanthins‐rich extract and rhinacanthin C ameliorate oxidative stress and inflammation in streptozotocin‐nicotinamide‐induced diabetic nephropathy
Abstract
In this present study, rhinacanthins-rich extract (RRE) and rhinacanthin C (RC) the main bioactive constituent of Rhinacanthus nasutus was investigated for their protective effect against diabetic nephropathy (DN). Diabetes was induced by administering nicotinamide (100 mg/kg, i.p.)/streptozotocin (60 mg/kg, i.p.) and diabetic rats were orally administered with RRE and RC for 4 weeks. RRE and RC significantly reduced the kidney index, renal...
Paper Details
Title
Rhinacanthins‐rich extract and rhinacanthin C ameliorate oxidative stress and inflammation in streptozotocin‐nicotinamide‐induced diabetic nephropathy
Published Date
Feb 18, 2019
Journal
Volume
43
Issue
4
Pages
e12812 - e12812
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