Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity.

Volume: 48, Issue: 5, Pages: 685 - 696
Published: Mar 11, 2019
Abstract
Summary null null Lysosomes and mitochondria are both crucial cellular organelles for metabolic homeostasis and organism health. However, mechanisms linking their metabolic activities to promote organism longevity remain poorly understood. We discovered that the induction of specific lysosomal signaling mediated by a LIPL-4 lysosomal acid lipase and its lipid chaperone LBP-8 increases mitochondrial s-oxidation to reduce lipid storage and promote...
Paper Details
Title
Lysosomal Signaling Promotes Longevity by Adjusting Mitochondrial Activity.
Published Date
Mar 11, 2019
Volume
48
Issue
5
Pages
685 - 696
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.