Abstract TP43: Evaluating the Generalizability of the Common Odds Ratio: A Demonstration using Two Trials of Endovascular Therapy

Introduction: The modified Rankin Scale (mRS) is an ordinal outcome, ranging from 0 (no symptoms) to 6 (death). Recent literature has demonstrated a preference for statistical analysis which maintains the ordinal nature of the scale. The proportional odds (PO) model assumes a single common odds ratio (OR) for all order-preserving dichotomizations of the outcome, but the validity of this assumption cannot be known in advance. The aim of this...