RAB1B interacts with TRAF3 to promote antiviral innate immunity
Abstract
null Nucleic acid-based antiviral innate immunity activates a signaling cascade that induces type I and type III interferons (IFNs), and other cytokines. This signaling, which is highly regulated, is initiated by pattern recognition receptors, such as RIG-I, that sense viral RNA and then signal to the adaptor protein, MAVS. This adaptor protein then recruits additional signaling proteins, including TRAF3 and TBK1, to form a signaling complex...
Paper Details
Title
RAB1B interacts with TRAF3 to promote antiviral innate immunity
Published Date
Feb 5, 2019
Journal
Pages
542050
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