A Role for Postsynaptic Density 95 and Its Binding Partners in Models of Traumatic Brain Injury
Abstract
Postsynaptic density 95 (PSD-95), the major scaffold protein at excitatory synapses, plays a major role in mediating intracellular signaling by synaptic N-methyl-d-aspartate (NMDA) type glutamate receptors. Despite the fact that much is known about the role of PSD-95 in NMDA-mediated toxicity, less is known about its role in mechanical injury, and more specifically, in traumatic brain injury (TBI). Given that neural circuitry is disrupted after...
Paper Details
Title
A Role for Postsynaptic Density 95 and Its Binding Partners in Models of Traumatic Brain Injury
Published Date
Jul 1, 2019
Journal
Volume
36
Issue
13
Pages
2129 - 2138
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