Cadaverine, a metabolite of the microbiome, reduces breast cancer aggressiveness through trace amino acid receptors
Abstract
Recent studies showed that changes to the gut microbiome alters the microbiome-derived metabolome, potentially promoting carcinogenesis in organs that are distal to the gut. In this study, we assessed the relationship between breast cancer and cadaverine biosynthesis. Cadaverine treatment of Balb/c female mice (500 nmol/kg p.o. q.d.) grafted with 4T1 breast cancer cells ameliorated the disease (lower mass and infiltration of the primary tumor,...
Paper Details
Title
Cadaverine, a metabolite of the microbiome, reduces breast cancer aggressiveness through trace amino acid receptors
Published Date
Feb 4, 2019
Journal
Volume
9
Issue
1
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