Debate: Looking forward: choose data over opinions to best serve youth with bipolar spectrum disorders – commentary on Parry et al. (2018)

Published on Feb 1, 2019in Child and Adolescent Mental Health1.439
· DOI :10.1111/camh.12296
Anna Van Meter9
Estimated H-index: 9
(The Feinstein Institute for Medical Research),
Ana Lúcia R. Moreira2
Estimated H-index: 2
(University of Lisbon),
Eric A. Youngstrom60
Estimated H-index: 60
(UNC: University of North Carolina at Chapel Hill)
  • References (12)
  • Citations (1)
#1Benjamin I. Goldstein (U of T: University of Toronto)H-Index: 41
#2Boris Birmaher (University of Pittsburgh)H-Index: 93
Last. Eric A. Youngstrom (UNC: University of North Carolina at Chapel Hill)H-Index: 60
view all 18 authors...
Objectives: Over the past two decades there has been tremendous growth in research regarding bipolar disorder (BD) among children and adolescents (i.e., pediatric BD; PBD). The primary purpose of this article is to distill the extant literature, dispel myths or exaggerated assertions in the field, and disseminate clinically relevant findings. Methods: An international group of experts completed a selective review of the literature, emphasizing areas of consensus, identifying limitations and gaps...
30 CitationsSource
#1Pedro Mario Pan (UNIFESP: Federal University of São Paulo)H-Index: 16
#2Giovanni Abrahão Salum (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 25
Last. Rodrigo A. Bressan (UNIFESP: Federal University of São Paulo)H-Index: 34
view all 14 authors...
Objective The purpose of the study was to define the latent structure of parent-reported manic symptoms and their association with functional impairment and familial risk in a community sample of Brazilian children. Method We screened for manic symptoms in a community sample of 2,512 children 6 to 12 years of age. Parents of children with "episodes of going abnormally high" completed a detailed mania section (n = 479; 19.1%). Confirmatory factor analysis (CFA) tested a solution with "Under-Contr...
10 CitationsSource
#1Ross J. Baldessarini (Harvard University)H-Index: 102
#2Leonardo Tondo (Harvard University)H-Index: 54
Last. Mauricio Tohen (University of Texas Health Science Center at San Antonio)H-Index: 84
view all 15 authors...
Early onset in bipolar disorder (BPD) has been associated with greater familial risk and unfavorable clinical outcomes. We pooled data from seven international centers to analyze the relationships of family history and symptomatic as well as functional measures of adult morbidity to onset age, or onset in childhood (age adolescent > child. Onset in childhood versus adolescence had more episodes/year and more psychiatric co-morbidity. Family history was most prevalent with childhood onset, simila...
75 CitationsSource
#1David C. Rettew (UVM: University of Vermont)H-Index: 29
#2Alicia Doyle Lynch (Tufts University)H-Index: 4
Last. Masha Y. Ivanova (UVM: University of Vermont)H-Index: 24
view all 5 authors...
Standardized diagnostic interviews (SDIs) have become de facto gold standards for clinical research. However, because clinical practitioners seldom use SDIs, it is essential to determine how well SDIs agree with clinical diagnoses. In meta-analyses of 38 articles published from 1995 to 2006 (N = 15,967 probands), mean kappas (z-transformed) between diagnoses from clinical evaluations versus SDIs were 0.27 for a broad category of all disorders, 0.29 for externalizing disorders, and 0.28 for inter...
150 CitationsSource
#1Boris Birmaher (University of Pittsburgh)H-Index: 93
#2David AxelsonH-Index: 60
Last. Martin B. KellerH-Index: 118
view all 16 authors...
Objective: The authors sought to assess the longitudinal course of youths with bipolar spectrum disorders over a 4-year period. Method: At total of 413 youths (ages 7–17 years) with bipolar I disorder (N=244), bipolar II disorder (N=28), and bipolar disorder not otherwise specified (N=141) were enrolled in the study. Symptoms were ascertained retrospectively on average every 9.4 months for 4 years using the Longitudinal Interval Follow-Up Evaluation. Rates and time to recovery and recurrence and...
288 CitationsSource
#1Eric A. Youngstrom (UNC: University of North Carolina at Chapel Hill)H-Index: 60
#2Boris Birmaher (University of Pittsburgh)H-Index: 93
Last. Robert L. Findling (Case Western Reserve University)H-Index: 72
view all 3 authors...
Bipolar disorder (BD) in children and adolescents has been a controversial topic that has received a great deal of recent scholarly and popular interest. There has been a tremendous increase in the number of trade books, articles in the popular media, and even television shows on the topic of BD (1), and there has been a similar rise in the rate at which it is being diagnosed and treated in youths. Although it was once considered primarily an adult-onset disorder, more than 100,000 children were...
152 CitationsSource
Clinical predictions made by mental health practitioners are compared with those using statistical approaches. Sixty-seven studies were identified from a comprehensive search of 56 years of research; 92 effect sizes were derived from these studies. The overall effect of clinical versus statistical prediction showed a somewhat greater accuracy for statistical methods. The most stringent sample of studies, from which 48 effect sizes were extracted, indicated a 13% increase in accuracy using statis...
344 CitationsSource
#1Eric A. Youngstrom (Case Western Reserve University)H-Index: 60
#2Robert L. Findling (Case Western Reserve University)H-Index: 72
Last. Joseph R. Calabrese (Case Western Reserve University)H-Index: 75
view all 3 authors...
Abstract Background Little is known about the extent to which manic symptoms might influence the self-report ratings of adolescents as compared to parent and teacher ratings, although there are clinical reasons to believe that mania would increase disagreement. Methods Parents and youths between the ages of 11 and 17 years were evaluated with the Schedule for Affective Disorders and Schizophrenia for School-Age Children (KSADS), Young Mania Rating Scale, and Child Depression Rating Scale-Revised...
60 CitationsSource
#1Roy H. Perlis (Harvard University)H-Index: 68
#2Sachiko Miyahara (University of Pittsburgh)H-Index: 27
Last. Andrew A. Nierenberg (Harvard University)H-Index: 87
view all 9 authors...
Abstract Background Early onset of mood symptoms in bipolar disorder has been associated with poor outcome in many studies; however, the factors that might contribute to poor outcome have not been adequately investigated. Methods The first consecutive 1000 adult bipolar patients enrolled in the National Institute of Mental Health's Systematic Treatment Enhancement Program for Bipolar Disorder were assessed at study entry to determine details of their age of onset of mood symptoms. Clinical cours...
612 CitationsSource
#1Jennifer D. Lish (UPenn: University of Pennsylvania)H-Index: 16
#2Susan Dime-MeenanH-Index: 1
Last. Robert M. A. Hirschfeld (UTMB: University of Texas Medical Branch)H-Index: 74
view all 5 authors...
Abstract Members of the National Depressive and Manic-Depressive Association who have bipolar disorder were surveyed. 59% of respondents had their first symptoms during childhood or adolence. Long delays between symptom onset, treatment-seeking, and receipt of a bipolar diagnosis were common. 45% of respondents currently experience frequent recurrences. Child/adolescent onset was associated with a positive family history, depressive or mixed initial symptoms, and frequent recurrence, with predom...
699 CitationsSource
Cited By1
#1Benjamin I. Goldstein (U of T: University of Toronto)H-Index: 41
#2Robert M. Post (GW: George Washington University)H-Index: 117
Last. Boris Birmaher (University of Pittsburgh)H-Index: 93
view all 3 authors...