Original paper
Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice
Abstract
Retinoid X receptors (RXRs) play an important role in transcription, are involved in numerous cellular networks from cell proliferation to lipid metabolism and are essential for normal eye development. RXRs form homo or heterodimers with other nuclear receptors, bind to DNA response elements and regulate several biological processes including neurogenesis. Mounting evidence suggests that RXR activation by selective RXR modulators (sRXRms) may be...
Paper Details
Title
Retinoid x receptor modulation protects against ER stress response and rescues glaucoma phenotypes in adult mice
Published Date
Apr 1, 2019
Journal
Volume
314
Pages
111 - 125
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Notes
History