Therapeutic drug Monitoring of Darunavir/Ritonavir in Pregnancy
Abstract
Background Physiological changes during pregnancy can have a significant impact on antiretroviral pharmacokinetics (PK), which may result in reduced drug efficacy. Here we describe the PK of darunavir/ritonavir (DRV/r) 800/100 once daily in a cohort of pregnant women undergoing routine therapeutic drug monitoring (TDM) as well as transplacental passage of DRV by measuring and comparing cord blood and maternal blood samples at delivery. Methods...
Paper Details
Title
Therapeutic drug Monitoring of Darunavir/Ritonavir in Pregnancy
Published Date
Apr 1, 2018
Journal
Volume
24
Issue
3
Pages
229 - 233
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