Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis
Volume: 22, Pages: 101132 - 101132
Published: Apr 1, 2019
Abstract
Non-alcoholic fatty liver disease (NAFLD) is linked to obesity and insulin resistance and is the most prevalent chronic liver disease. During the development of obesity and NAFLD, mitochondria adapt to the increased lipid load in hepatocytes by increasing the rate of fatty acid oxidation. In concert with this, reactive species (RS) generation is increased, damaging hepatocytes and inducing inflammation. Hepatic mitochondrial dysfunction is...
Paper Details
Title
Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis
Published Date
Apr 1, 2019
Volume
22
Pages
101132 - 101132
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