Conformations and cryo-force spectroscopy of spray-deposited single-strand DNA on gold
Abstract
Cryo-electron microscopy can determine the structure of biological matter in vitrified liquids. However, structure alone is insufficient to understand the function of native and engineered biomolecules. So far, their mechanical properties have mainly been probed at room temperature using tens of pico-newton forces with a resolution limited by thermal fluctuations. Here we combine force spectroscopy and computer simulations in cryogenic...
Paper Details
Title
Conformations and cryo-force spectroscopy of spray-deposited single-strand DNA on gold
Published Date
Feb 8, 2019
Journal
Volume
10
Issue
1
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History